MIS12 (NM_024039) Human Recombinant Protein
Product Specifications
Background
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis (PubMed:12515822, PubMed:15502821, PubMed:16585270) . Essential for proper kinetochore microtubule attachments (PubMed:23891108) .[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human MIS12, MIND kinetochore complex component, homolog (yeast) (MIS12)
Synonyms
2510025F08Rik; hMis12; KNTC2AP; MTW1
Gene ID
79003
UniProt
Q9H081, A8K1M4
Accession Number mRNA
NM_024039
Chromosomal Location
17p13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
24 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MIS12
Species
Human
Protein ID
NP_076944
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/79003
Uniprot URL
https://www.uniprot.org/uniprot/Q9H081
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_024039
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_076944
Curated Selection
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