CUEDC2 (NM_024040) Human Recombinant Protein
Product Specifications
Background
Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human CUE domain containing 2 (CUEDC2)
Synonyms
BA18I14.5; C10orf66
Gene ID
79004
UniProt
Q9H467
Accession Number mRNA
NM_024040
Chromosomal Location
10q24.32
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
31.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CUEDC2
Species
Human
Protein ID
NP_076945
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/79004
Uniprot URL
https://www.uniprot.org/uniprot/Q9H467
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_024040
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_076945
Curated Selection
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