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HYPK (NM_016400) Human Recombinant Protein

Product Specifications

Background

Has a chaperone-like activity preventing polyglutamine (polyQ) aggregation of HTT. Protects against HTT polyQ-mediated apoptosis in Neuro2a neuronal cells. Required for optimal NAA10-NAA15 complex-mediated N-terminal acetylation.[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human Huntingtin interacting protein K (HYPK)

Synonyms

C15orf63; HSPC136

Gene ID

25764

UniProt

Q9NX55, A0A024R5Q1

Accession Number mRNA

NM_016400

Chromosomal Location

15q15.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

14.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

HYPK

Species

Human

Protein ID

NP_057484

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/25764

Uniprot URL

https://www.uniprot.org/uniprot/Q9NX55

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_016400

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_057484

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