HYPK (NM_016400) Human Recombinant Protein
Product Specifications
Background
Has a chaperone-like activity preventing polyglutamine (polyQ) aggregation of HTT. Protects against HTT polyQ-mediated apoptosis in Neuro2a neuronal cells. Required for optimal NAA10-NAA15 complex-mediated N-terminal acetylation.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human Huntingtin interacting protein K (HYPK)
Synonyms
C15orf63; HSPC136
Gene ID
25764
UniProt
Q9NX55, A0A024R5Q1
Accession Number mRNA
NM_016400
Chromosomal Location
15q15.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
14.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HYPK
Species
Human
Protein ID
NP_057484
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/25764
Uniprot URL
https://www.uniprot.org/uniprot/Q9NX55
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_016400
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_057484
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