METTL3 (NM_019852) Human Recombinant Protein
Product Specifications
Background
This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human methyltransferase like 3 (METTL3)
Synonyms
HMETTL3; IME4; M6A; MT-A70; Spo8
Gene ID
56339
UniProt
Q86U44
Accession Number mRNA
NM_019852
Chromosomal Location
14q11.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
64.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
METTL3
Species
Human
Protein ID
NP_062826
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/56339
Uniprot URL
https://www.uniprot.org/uniprot/Q86U44
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_019852
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_062826
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