SFXN3 (NM_030971) Human Recombinant Protein
Product Specifications
Background
Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway (PubMed:30442778) . Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors (PubMed:30442778) .[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human sideroflexin 3 (SFXN3)
Synonyms
BA108L7.2; SFX3; SLC56A3
Gene ID
81855
UniProt
Q9BWM7, A0A1P0AYU5
Accession Number mRNA
NM_030971
Chromosomal Location
10q24.31
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
35.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SFXN3
Species
Human
Protein ID
NP_112233
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/81855
Uniprot URL
https://www.uniprot.org/uniprot/Q9BWM7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_030971
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_112233
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