PDXK (NM_003681) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human pyridoxal (pyridoxine, vitamin B6) kinase (PDXK)

Synonyms

C21orf97; C21orf124; HEL-S-1a; HMSN6C; PKH; PNK; PRED79

Gene ID

8566

UniProt

O00764, V9HWC3

Accession Number mRNA

NM_003681

Chromosomal Location

21q22.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Metabolic pathways, Vitamin B6 metabolism

Field of Research

Metabolic pathways, Vitamin B6 metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

34.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.