PDXK (NM_003681) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Synonyms
C21orf97; C21orf124; HEL-S-1a; HMSN6C; PKH; PNK; PRED79
Gene ID
8566
UniProt
O00764, V9HWC3
Accession Number mRNA
NM_003681
Chromosomal Location
21q22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Metabolic pathways, Vitamin B6 metabolism
Field of Research
Metabolic pathways, Vitamin B6 metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
34.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PDXK
Species
Human
Protein ID
NP_003672
Overview
Recombinant protein of human pyridoxal (pyridoxine, vitamin B6) kinase (PDXK)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8566
Uniprot URL
https://www.uniprot.org/uniprot/O00764
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003681
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003672
Curated Selection
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