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PTDSS1 (NM_014754) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene catalyzes the formation of phosphatidylserine from either phosphatidylcholine or phosphatidylethanolamine. Phosphatidylserine localizes to the mitochondria-associated membrane of the endoplasmic reticulum, where it serves a structural role as well as a signaling role. Defects in this gene are a cause of Lenz-Majewski hyperostotic dwarfism. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014]

Overview

Recombinant protein of human phosphatidylserine synthase 1 (PTDSS1)

Synonyms

LMHD; PSS1; PSSA

Gene ID

9791

UniProt

P48651

Accession Number mRNA

NM_014754

Chromosomal Location

8q22.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Glycerophospholipid metabolism, Metabolic pathways

Field of Research

Glycerophospholipid metabolism, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transmembrane

Molecular Weight

55.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PTDSS1

Species

Human

Protein ID

NP_055569

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9791

Uniprot URL

https://www.uniprot.org/uniprot/P48651

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_014754

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_055569

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