PSMC3IP (NM_013290) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that functions in meiotic recombination. It is a subunit of the PSMC3IP/MND1 complex, which interacts with PSMC3/TBP1 to stimulate DMC1- and RAD51-mediated strand exchange during meiosis. The protein encoded by this gene can also co-activate ligand-driven transcription mediated by estrogen, androgen, glucocorticoid, progesterone, and thyroid nuclear receptors. Mutations in this gene cause XX female gonadal dysgenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2011]
Synonyms
GT198; HOP2; HUMGT198A; ODG3; TBPIP
Gene ID
29893
UniProt
Q9P2W1
Accession Number mRNA
NM_013290
Chromosomal Location
17q21.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
23.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PSMC3IP
Species
Human
Protein ID
NP_037422
Overview
Recombinant protein of human PSMC3 interacting protein (PSMC3IP), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/29893
Uniprot URL
https://www.uniprot.org/uniprot/Q9P2W1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_013290
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_037422
Curated Selection
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