KIF20A (NM_005733) Human Recombinant Protein

Product Specifications

Background

Mitotic kinesin required for chromosome passenger complex (CPC) -mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP) -bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human kinesin family member 20A (KIF20A)

Synonyms

MKLP2; RAB6KIFL

Gene ID

10112

UniProt

O95235

Accession Number mRNA

NM_005733

Chromosomal Location

5q31.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

100.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.