AP2B1 (NM_001030006) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human adaptor-related protein complex 2, beta 1 subunit (AP2B1), transcript variant 1
Synonyms
ADTB2; AP2-BETA; AP105B; CLAPB1
Gene ID
163
UniProt
P63010, A0A140VJE8, Q96EL6
Accession Number mRNA
NM_001030006
Chromosomal Location
17q12
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Endocytosis, Huntington's disease
Field of Research
Endocytosis, Huntington's disease
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
105.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
AP2B1
Species
Human
Protein ID
NP_001025177
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/163
Uniprot URL
https://www.uniprot.org/uniprot/P63010
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001030006
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001025177
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