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AP2B1 (NM_001030006) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human adaptor-related protein complex 2, beta 1 subunit (AP2B1), transcript variant 1

Synonyms

ADTB2; AP2-BETA; AP105B; CLAPB1

Gene ID

163

UniProt

P63010, A0A140VJE8, Q96EL6

Accession Number mRNA

NM_001030006

Chromosomal Location

17q12

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Endocytosis, Huntington's disease

Field of Research

Endocytosis, Huntington's disease

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

105.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

AP2B1

Species

Human

Protein ID

NP_001025177

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/163

Uniprot URL

https://www.uniprot.org/uniprot/P63010

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001030006

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001025177

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