ASS1 (NM_054012) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of this gene cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2012]

Overview

Recombinant protein of human argininosuccinate synthetase 1 (ASS1), transcript variant 2

Synonyms

ASS; CTLN1

Gene ID

445

UniProt

P00966, Q5T6L4

Accession Number mRNA

NM_054012

Chromosomal Location

9q34.11

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Metabolic pathways

Field of Research

Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

46.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ASS1

Species

Human

Protein ID

NP_446464

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/445

Uniprot URL

https://www.uniprot.org/uniprot/P00966

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_054012

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_446464

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