UBE2G1 (NM_003342) Human Recombinant Protein

Product Specifications

Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) (UBE2G1)

Synonyms

E217K; UBC7; UBE2G

Gene ID

7326

UniProt

P62253

Accession Number mRNA

NM_003342

Chromosomal Location

17p13.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Parkinson's disease, Ubiquitin mediated proteolysis

Field of Research

Parkinson's disease, Ubiquitin mediated proteolysis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

19.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.