SNURPORTIN1 (SNUPN) (NM_001042588) Human Recombinant Protein
Product Specifications
Background
The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
Synonyms
KPNBL; RNUT1; Snurportin1
Gene ID
10073
UniProt
O95149
Accession Number mRNA
NM_001042588
Chromosomal Location
15q24.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
41 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SNUPN
Species
Human
Protein ID
NP_001036053
Overview
Recombinant protein of human snurportin 1 (SNUPN), transcript variant 3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10073
Uniprot URL
https://www.uniprot.org/uniprot/O95149
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001042588
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001036053
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