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Perilipin 3 (PLIN3) (NM_005817) Human Recombinant Protein

Product Specifications

Background

Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2009]

Overview

Recombinant protein of human mannose-6-phosphate receptor binding protein 1 (M6PRBP1)

Synonyms

M6PRBP1; PP17; TIP47

Gene ID

10226

UniProt

O60664

Accession Number mRNA

NM_005817

Chromosomal Location

19p13.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

46.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PLIN3

Species

Human

Protein ID

NP_005808

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/10226

Uniprot URL

https://www.uniprot.org/uniprot/O60664

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005817

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005808

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