Perilipin 3 (PLIN3) (NM_005817) Human Recombinant Protein
Product Specifications
Background
Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2009]
Synonyms
M6PRBP1; PP17; TIP47
Gene ID
10226
UniProt
O60664
Accession Number mRNA
NM_005817
Chromosomal Location
19p13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
46.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PLIN3
Species
Human
Protein ID
NP_005808
Overview
Recombinant protein of human mannose-6-phosphate receptor binding protein 1 (M6PRBP1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10226
Uniprot URL
https://www.uniprot.org/uniprot/O60664
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005817
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005808
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