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GET3 (NM_004317) Human Recombinant Protein

Selected Variant

PH41573M5

Size: 20 µg

Product Specifications

Background

This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER) . It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion. [provided by RefSeq, Oct 2011]

Overview

Recombinant protein of human arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) (ASNA1)

Synonyms

ARSA-I; ARSA1; ASNA-I; ASNA1; TRC40

Gene ID

439

UniProt

O43681

Accession Number mRNA

NM_004317

Chromosomal Location

19p13.13

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

38.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

GET3

Species

Human

Protein ID

NP_004308

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/439

Uniprot URL

https://www.uniprot.org/uniprot/O43681

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004317

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004308

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