Prohibitin (PHB) (NM_002634) Human Recombinant Protein
Product Specifications
Background
This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Synonyms
HEL-215; HEL-S-54e; PHB1
Gene ID
5245
UniProt
P35232, A8K401, Q53FV0
Accession Number mRNA
NM_002634
Chromosomal Location
17q21.33
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Stem cell - Pluripotency, Transcription Factors
Molecular Weight
29.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PHB
Species
Human
Protein ID
NP_002625
Overview
Recombinant protein of human prohibitin (PHB)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5245
Uniprot URL
https://www.uniprot.org/uniprot/P35232
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002634
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002625
Curated Selection
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