Calbindin (CALB1) (NM_004929) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. It contains four active calcium-binding domains, and has two modified domains that are thought to have lost their calcium binding capability. This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease. [provided by RefSeq, Jan 2015]
Synonyms
CALB; D-28K
Gene ID
793
UniProt
P05937
Accession Number mRNA
NM_004929
Chromosomal Location
8q21.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
29.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CALB1
Species
Human
Protein ID
NP_004920
Overview
Recombinant protein of human calbindin 1, 28kDa (CALB1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/793
Uniprot URL
https://www.uniprot.org/uniprot/P05937
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004929
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004920
Curated Selection
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