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Calbindin (CALB1) (NM_004929) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. It contains four active calcium-binding domains, and has two modified domains that are thought to have lost their calcium binding capability. This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease. [provided by RefSeq, Jan 2015]

Overview

Recombinant protein of human calbindin 1, 28kDa (CALB1)

Synonyms

CALB; D-28K

Gene ID

793

UniProt

P05937

Accession Number mRNA

NM_004929

Chromosomal Location

8q21.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

29.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CALB1

Species

Human

Protein ID

NP_004920

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/793

Uniprot URL

https://www.uniprot.org/uniprot/P05937

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004929

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004920

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