GADD45G (NM_006705) Human Recombinant Protein
Product Specifications
Background
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human growth arrest and DNA-damage-inducible, gamma (GADD45G)
Synonyms
CR6; DDIT2; GADD45gamma; GRP17
Gene ID
10912
UniProt
O95257
Accession Number mRNA
NM_006705
Chromosomal Location
9q22.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Cell cycle, MAPK signaling pathway, p53 signaling pathway
Field of Research
Cell cycle, MAPK signaling pathway, p53 signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
16.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GADD45G
Species
Human
Protein ID
NP_006696
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10912
Uniprot URL
https://www.uniprot.org/uniprot/O95257
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006705
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006696
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