FDFT1 (NM_004462) Human Recombinant Protein
Product Specifications
Background
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human farnesyl-diphosphate farnesyltransferase 1 (FDFT1)
Synonyms
DGPT; ERG9; SQS; SQSD; SS
Gene ID
2222
UniProt
P37268, Q6IAX1
Accession Number mRNA
NM_004462
Chromosomal Location
8p23.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Metabolic pathways, Steroid biosynthesis
Field of Research
Metabolic pathways, Steroid biosynthesis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
47.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FDFT1
Species
Human
Protein ID
NP_004453
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2222
Uniprot URL
https://www.uniprot.org/uniprot/P37268
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004462
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004453
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