PLEK2 (NM_016445) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene associates with membrane-bound phosphatidylinositols generated by phosphatidylinositol 3-kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1, q subcomponent, B chain (C1QB), this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease. [provided by RefSeq, Dec 2015]
Synonyms
Pleckstrin 2; pleckstrin 2 homolog
Gene ID
26499
UniProt
Q9NYT0
Accession Number mRNA
NM_016445
Chromosomal Location
14q23.3-q24.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
39.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PLEK2
Species
Human
Protein ID
NP_057529
Overview
Recombinant protein of human pleckstrin 2 (PLEK2)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/26499
Uniprot URL
https://www.uniprot.org/uniprot/Q9NYT0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_016445
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_057529
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