POLR1D (NM_015972) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in this gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011]

Overview

Recombinant protein of human polymerase (RNA) I polypeptide D, 16kDa (POLR1D), transcript variant 1

Synonyms

AC19; POLR1C; RPA9; RPA16; RPAC2; RPC16; RPO1-3; TCS2

Gene ID

51082

UniProt

P0DPB6

Accession Number mRNA

NM_015972

Chromosomal Location

13q12.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Cytosolic DNA-sensing pathway, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase

Field of Research

Cytosolic DNA-sensing pathway, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Stem cell - Pluripotency, Transcription Factors

Molecular Weight

15.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

POLR1D

Species

Human

Protein ID

NP_057056

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/51082

Uniprot URL

https://www.uniprot.org/uniprot/P0DPB6

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_015972

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_057056

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

E103630 1 Each

Human IZUM1 ELISA Kit

Ask

View Details

PPT-16106 100 µg

Human ZC3H12D Recombinant Protein

Ask

View Details

RC220766A1V 250 µL

Human TP53I11 (NM_001076787) AAV Particle

Ask

View Details

NBP3-27822-100ul 100 µL

Rabbit Monoclonal MYO19 Antibody (SR4212)

Ask

View Details

TP721583 10 µg

CASR Human Recombinant Protein, Synthetic Nanodisc

Ask

View Details