PPP2R3C (NM_017917) Human Recombinant Protein
Product Specifications
Background
This gene encodes a regulatory subunit of the serine/threonine phosphatase, protein phosphatase 2. This protein is localized to both nuclear and cytoplasmic regions depending on cell cycle phase. Homozygous conditional knockout mice for this gene exhibit reduced numbers and impaired proliferation of immune system B cells. This protein may regulate the expression of the P-glycoprotein ATP-binding cassette transporter through its phosphatase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Overview
Recombinant protein of human protein phosphatase 2 (formerly 2A), regulatory subunit B'', gamma (PPP2R3C)
Synonyms
C14orf10; G4-1; G5pr; GDRM; SPGF36
Gene ID
55012
UniProt
Q969Q6
Accession Number mRNA
NM_017917
Chromosomal Location
14q13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
53.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PPP2R3C
Species
Human
Protein ID
NP_060387
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/55012
Uniprot URL
https://www.uniprot.org/uniprot/Q969Q6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_017917
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060387
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