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PPP2R3C (NM_017917) Human Recombinant Protein

Product Specifications

Background

This gene encodes a regulatory subunit of the serine/threonine phosphatase, protein phosphatase 2. This protein is localized to both nuclear and cytoplasmic regions depending on cell cycle phase. Homozygous conditional knockout mice for this gene exhibit reduced numbers and impaired proliferation of immune system B cells. This protein may regulate the expression of the P-glycoprotein ATP-binding cassette transporter through its phosphatase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

Overview

Recombinant protein of human protein phosphatase 2 (formerly 2A), regulatory subunit B'', gamma (PPP2R3C)

Synonyms

C14orf10; G4-1; G5pr; GDRM; SPGF36

Gene ID

55012

UniProt

Q969Q6

Accession Number mRNA

NM_017917

Chromosomal Location

14q13.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

53.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PPP2R3C

Species

Human

Protein ID

NP_060387

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/55012

Uniprot URL

https://www.uniprot.org/uniprot/Q969Q6

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_017917

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_060387

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