RALBP1 (NM_006788) Human Recombinant Protein

Product Specifications

Background

RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550) . Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS; MIM 190020) (summary by Feig, 2003 [PubMed 12888294]) .[supplied by OMIM, Nov 2010]

Overview

Recombinant protein of human ralA binding protein 1 (RALBP1)

Synonyms

RIP1; RLIP1; RLIP76

Gene ID

10928

UniProt

Q15311

Accession Number mRNA

NM_006788

Chromosomal Location

18p11.22

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Pancreatic cancer, Pathways in cancer

Field of Research

Pancreatic cancer, Pathways in cancer

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

75.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.