N myc interactor (NMI) (NM_004688) Human Recombinant Protein
Product Specifications
Background
NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. [provided by RefSeq, Jul 2008]
Synonyms
N-myc (and STAT) interactor; N-myc-interactor; N-myc and STAT interactor; N-myc interactor
Gene ID
9111
UniProt
Q13287
Accession Number mRNA
NM_004688
Chromosomal Location
2q23.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
34.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NMI
Species
Human
Protein ID
NP_004679
Overview
Recombinant protein of human N-myc (and STAT) interactor (NMI)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9111
Uniprot URL
https://www.uniprot.org/uniprot/Q13287
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004688
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004679
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