PRP18 homolog (PRPF18) (NM_003675) Human Recombinant Protein
Product Specifications
Background
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by RefSeq, Jul 2008]
Synonyms
HPrp18; PRP18
Gene ID
8559
UniProt
Q99633
Accession Number mRNA
NM_003675
Chromosomal Location
10p13
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Spliceosome
Field of Research
Spliceosome
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
39.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PRPF18
Species
Human
Protein ID
NP_003666
Overview
Recombinant protein of human PRP18 pre-mRNA processing factor 18 homolog (S. cerevisiae) (PRPF18)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8559
Uniprot URL
https://www.uniprot.org/uniprot/Q99633
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003675
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003666
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