MNAT1 (NM_002431) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene, along with cyclin H and CDK7, forms the CDK-activating kinase (CAK) enzymatic complex. This complex activates several cyclin-associated kinases and can also associate with TFIIH to activate transcription by RNA polymerase II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Overview

Recombinant protein of human menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) (MNAT1)

Synonyms

CAP35; MAT1; RNF66; TFB3

Gene ID

4331

UniProt

P51948, A0A024R688

Accession Number mRNA

NM_002431

Chromosomal Location

14q23.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Nucleotide excision repair

Field of Research

Nucleotide excision repair

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Stem cell - Pluripotency, Transcription Factors

Molecular Weight

35.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.