Lamin B1 (LMNB1) (NM_005573) Human Recombinant Protein

Product Specifications

Background

This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD) . Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Overview

Recombinant protein of human lamin B1 (LMNB1)

Synonyms

ADLD; LMN; LMN2; LMNB; MCPH26

Gene ID

4001

UniProt

P20700

Accession Number mRNA

NM_005573

Chromosomal Location

5q23.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Activity

27079252

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

66.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.