Lamin B1 (LMNB1) (NM_005573) Human Recombinant Protein
Product Specifications
Background
This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD) . Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Overview
Recombinant protein of human lamin B1 (LMNB1)
Synonyms
ADLD; LMN; LMN2; LMNB; MCPH26
Gene ID
4001
UniProt
P20700
Accession Number mRNA
NM_005573
Chromosomal Location
5q23.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
27079252
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
66.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
LMNB1
Species
Human
Protein ID
NP_005564
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4001
Uniprot URL
https://www.uniprot.org/uniprot/P20700
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005573
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005564
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