Proteasome 20S beta 6 (PSMB6) (NM_002798) Human Recombinant Protein
Product Specifications
Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Synonyms
DELTA; LMPY; Y
Gene ID
5694
UniProt
P28072, Q6IAT9
Accession Number mRNA
NM_002798
Chromosomal Location
17p13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Proteasome
Field of Research
Proteasome
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protease
Molecular Weight
25.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PSMB6
Species
Human
Protein ID
NP_002789
Overview
Recombinant protein of human proteasome (prosome, macropain) subunit, beta type, 6 (PSMB6)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5694
Uniprot URL
https://www.uniprot.org/uniprot/P28072
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002798
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002789
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items