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Proteasome 20S beta 6 (PSMB6) (NM_002798) Human Recombinant Protein

Product Specifications

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Overview

Recombinant protein of human proteasome (prosome, macropain) subunit, beta type, 6 (PSMB6)

Synonyms

DELTA; LMPY; Y

Gene ID

5694

UniProt

P28072, Q6IAT9

Accession Number mRNA

NM_002798

Chromosomal Location

17p13.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Proteasome

Field of Research

Proteasome

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Protease

Molecular Weight

25.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PSMB6

Species

Human

Protein ID

NP_002789

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/5694

Uniprot URL

https://www.uniprot.org/uniprot/P28072

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002798

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002789

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