PDK4 (NM_002612) Human Recombinant Protein
Product Specifications
Background
This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin. [provided by RefSeq, Jul 2008]
Synonyms
FLJ40832
Gene ID
5166
UniProt
Q16654, A4D1H4
Accession Number mRNA
NM_002612
Chromosomal Location
7q21.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase
Molecular Weight
46.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PDK4
Species
Human
Protein ID
NP_002603
Overview
Recombinant protein of human pyruvate dehydrogenase kinase, isozyme 4 (PDK4)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5166
Uniprot URL
https://www.uniprot.org/uniprot/Q16654
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002612
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002603
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6492150-01 0.2 mL
PARP3, CT (NAD+ ADP-ribosyltransferase 3 PARP-3, Putative Uncharacterized Protein, Adprtl3) (Biotin)
Ask
View Details 
MBS6492150-02 5x 0.2 mL
PARP3, CT (NAD+ ADP-ribosyltransferase 3 PARP-3, Putative Uncharacterized Protein, Adprtl3) (Biotin)
Ask
View Details 
