CMBL (NM_138809) Human Recombinant Protein
Selected Variant
PH41270M5
Size: 20 µg
Product Specifications
Background
CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]) .[supplied by OMIM, Apr 2010]
Overview
Recombinant protein of human carboxymethylenebutenolidase homolog (Pseudomonas) (CMBL)
Synonyms
JS-1
Gene ID
134147
UniProt
Q96DG6
Accession Number mRNA
NM_138809
Chromosomal Location
5p15.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Metabolic pathways
Field of Research
Metabolic pathways
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
27.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CMBL
Species
Human
Protein ID
NP_620164
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/134147
Uniprot URL
https://www.uniprot.org/uniprot/Q96DG6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_138809
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_620164
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