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Spermidine synthase (SRM) (NM_003132) Human Recombinant Protein

Product Specifications

Background

The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor. [provided by RefSeq, Jul 2008]

Synonyms

PAPT; SPDSY; SPS1; SRML1

Gene ID

6723

UniProt

P19623

Accession Number mRNA

NM_003132

Chromosomal Location

1p36.22

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Arginine and proline metabolism, beta-Alanine metabolism, Cysteine and methionine metabolism, Glutathione metabolism, Metabolic pathways

Field of Research

Arginine and proline metabolism, beta-Alanine metabolism, Cysteine and methionine metabolism, Glutathione metabolism, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

33.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SRM

Species

Human

Protein ID

NP_003123

Overview

Recombinant protein of human spermidine synthase (SRM)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6723

Uniprot URL

https://www.uniprot.org/uniprot/P19623

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_003132

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003123

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