AHA1 (AHSA1) (NM_012111) Human Recombinant Protein
Product Specifications
Background
Acts as a co-chaperone of HSP90AA1 (PubMed:29127155) . Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity (PubMed:29127155) . Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360) . Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:29127155) .[UniProtKB/Swiss-Prot Function]
Synonyms
AHA1; C14orf3; hAha1; p38
Gene ID
10598
UniProt
O95433
Accession Number mRNA
NM_012111
Chromosomal Location
14q24.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
38.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
AHSA1
Species
Human
Protein ID
NP_036243
Overview
Recombinant protein of human AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) (AHSA1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10598
Uniprot URL
https://www.uniprot.org/uniprot/O95433
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_012111
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_036243
Curated Selection
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