AHA1 (AHSA1) (NM_012111) Human Recombinant Protein

Product Specifications

Background

Acts as a co-chaperone of HSP90AA1 (PubMed:29127155) . Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity (PubMed:29127155) . Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360) . Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:29127155) .[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) (AHSA1)

Synonyms

AHA1; C14orf3; hAha1; p38

Gene ID

10598

UniProt

O95433

Accession Number mRNA

NM_012111

Chromosomal Location

14q24.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

38.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.