UBE2N (NM_003348) Human Recombinant Protein
Product Specifications
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication repair. [provided by RefSeq, Jul 2008]
Synonyms
HEL-S-71; UBC13; UbcH-ben; UbcH13; UBCHBEN
Gene ID
7334
UniProt
P61088, V9HW41
Accession Number mRNA
NM_003348
Chromosomal Location
12q22
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Ubiquitin mediated proteolysis
Field of Research
Ubiquitin mediated proteolysis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
17 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UBE2N
Species
Human
Protein ID
NP_003339
Overview
Recombinant protein of human ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) (UBE2N)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7334
Uniprot URL
https://www.uniprot.org/uniprot/P61088
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003348
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003339
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