FUS (NM_004960) Human Recombinant Protein
Selected Variant
PH41205M5
Size: 20 µg
Product Specifications
Background
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009]
Overview
Recombinant protein of human fusion (involved in t (12;16) in malignant liposarcoma) (FUS)
Synonyms
ALS6; altFUS; ETM4; FUS1; HNRNPP2; POMP75; TLS
Gene ID
2521
UniProt
P35637, Q6IBQ5
Accession Number mRNA
NM_004960
Chromosomal Location
16p11.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
262868272716493229513652
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Stem cell - Pluripotency
Molecular Weight
53.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FUS
Species
Human
Protein ID
NP_004951
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2521
Uniprot URL
https://www.uniprot.org/uniprot/P35637
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004960
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004951
Price
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