TRAP100 (MED24) (NM_014815) Human Recombinant Protein
Product Specifications
Background
This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human mediator complex subunit 24 (MED24), transcript variant 1
Synonyms
ARC100; CRSP4; CRSP100; DRIP100; MED5; THRAP4; TRAP100
Gene ID
9862
UniProt
O75448
Accession Number mRNA
NM_014815
Chromosomal Location
17q21.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
110.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MED24
Species
Human
Protein ID
NP_055630
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9862
Uniprot URL
https://www.uniprot.org/uniprot/O75448
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_014815
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055630
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