HMG20A (NM_018200) Human Recombinant Protein
Product Specifications
Background
Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4 (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
HMGX1; HMGXB1
Gene ID
10363
UniProt
Q9NP66
Accession Number mRNA
NM_018200
Chromosomal Location
15q24.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
40 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HMG20A
Species
Human
Protein ID
NP_060670
Overview
Recombinant protein of human high-mobility group 20A (HMG20A)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10363
Uniprot URL
https://www.uniprot.org/uniprot/Q9NP66
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_018200
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060670
Curated Selection
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