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DDX41 (NM_016222) Human Recombinant Protein

Product Specifications

Background

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a member of the DEAD box protein family and interacts with several spliceosomal proteins. In addition, the encoded protein may recognize the bacterial second messengers cyclic di-GMP and cyclic di-AMP, resulting in the induction of genes involved in the innate immune response. [provided by RefSeq, Jan 2017]

Overview

Recombinant protein of human DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 (DDX41)

Synonyms

ABS; MPLPF

Gene ID

51428

UniProt

Q9UJV9

Accession Number mRNA

NM_016222

Chromosomal Location

5q35.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

69.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

DDX41

Species

Human

Protein ID

NP_057306

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/51428

Uniprot URL

https://www.uniprot.org/uniprot/Q9UJV9

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_016222

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_057306

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