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POLR2K (NM_005034) Human Recombinant Protein

Product Specifications

Background

This gene encodes one of the smallest subunits of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa (POLR2K)

Synonyms

ABC10-alpha; hRPB7.0; hsRPB10a; RPABC4; RPB7.0; RPB10alpha; RPB12

Gene ID

5440

UniProt

P53803, A0A024R9G0

Accession Number mRNA

NM_005034

Chromosomal Location

8q22.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Huntington's disease, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase

Field of Research

Huntington's disease, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, RNA polymerase

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transcription Factors

Molecular Weight

6.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

POLR2K

Species

Human

Protein ID

NP_005025

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/5440

Uniprot URL

https://www.uniprot.org/uniprot/P53803

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005034

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005025

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