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PMM1 (NM_002676) Human Recombinant Protein

Product Specifications

Background

Phosphomannomutase catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose, which is essential for N-linked glycosylation and thus the secretion of several glycoproteins as well as for the synthesis of glycosyl-phosphatidyl-inositol (GPI) anchored proteins. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human phosphomannomutase 1 (PMM1)

Synonyms

PMM 1; PMMH-22; Sec53

Gene ID

5372

UniProt

Q92871, A0A024R1U5

Accession Number mRNA

NM_002676

Chromosomal Location

22q13.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Metabolic pathways

Field of Research

Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

29.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PMM1

Species

Human

Protein ID

NP_002667

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/5372

Uniprot URL

https://www.uniprot.org/uniprot/Q92871

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002676

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002667

Frequently Asked Questions

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