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TBCA (NM_004607) Human Recombinant Protein

Product Specifications

Background

The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Overview

Recombinant protein of human tubulin folding cofactor A (TBCA)

Gene ID

6902

UniProt

O75347, Q6FGD7

Accession Number mRNA

NM_004607

Chromosomal Location

5q14.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

12.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

TBCA

Species

Human

Protein ID

NP_004598

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6902

Uniprot URL

https://www.uniprot.org/uniprot/O75347

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004607

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004598

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