TBCA (NM_004607) Human Recombinant Protein
Product Specifications
Background
The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Overview
Recombinant protein of human tubulin folding cofactor A (TBCA)
Gene ID
6902
UniProt
O75347, Q6FGD7
Accession Number mRNA
NM_004607
Chromosomal Location
5q14.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
12.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TBCA
Species
Human
Protein ID
NP_004598
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6902
Uniprot URL
https://www.uniprot.org/uniprot/O75347
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004607
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004598
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