EZH2 (NM_004456) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
Synonyms
ENX-1; ENX1; EZH1; EZH2b; KMT6; KMT6A; WVS; WVS2
Gene ID
2146
UniProt
Q15910, A0A090N8E9
Accession Number mRNA
NM_004456
Chromosomal Location
7q36.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
261737102617371027869166
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
85.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
EZH2
Species
Human
Protein ID
NP_004447
Overview
Recombinant protein of human enhancer of zeste homolog 2 (Drosophila) (EZH2), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2146
Uniprot URL
https://www.uniprot.org/uniprot/Q15910
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004456
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004447
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