UCHL3 (NM_006002) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a member of the deubiquitinating enzyme family. Members of this family are proteases that catalyze the removal of ubiquitin from polypeptides and are divided into five classes, depending on the mechanism of catalysis. This protein may hydrolyze the ubiquitinyl-N-epsilon amide bond of ubiquitinated proteins to regenerate ubiquitin for another catalytic cycle. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
Synonyms
UCH-L3
Gene ID
7347
UniProt
P15374, A0A140VJZ4
Accession Number mRNA
NM_006002
Chromosomal Location
13q22.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protease
Molecular Weight
26 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UCHL3
Species
Human
Protein ID
NP_005993
Overview
Recombinant protein of human ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) (UCHL3)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7347
Uniprot URL
https://www.uniprot.org/uniprot/P15374
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006002
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005993
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