GPBB (PYGB) (NM_002862) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human phosphorylase, glycogen; brain (PYGB)

Synonyms

GPBB

Gene ID

5834

UniProt

P11216

Accession Number mRNA

NM_002862

Chromosomal Location

20p11.21

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Insulin signaling pathway, Starch and sucrose metabolism

Field of Research

Insulin signaling pathway, Starch and sucrose metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

96.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.