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FRA1 (FOSL1) (NM_005438) Human Recombinant Protein

Selected Variant

PH41047M5

Size: 20 µg

Product Specifications

Background

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Overview

Recombinant protein of human FOS-like antigen 1 (FOSL1)

Synonyms

FRA; fra-1; FRA1

Gene ID

8061

UniProt

P15407, A0A0S2Z595

Accession Number mRNA

NM_005438

Chromosomal Location

11q13.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Wnt signaling pathway

Field of Research

Wnt signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transcription Factors

Molecular Weight

29.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FOSL1

Species

Human

Protein ID

NP_005429

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/8061

Uniprot URL

https://www.uniprot.org/uniprot/P15407

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005438

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005429

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