SERPINB1 (NM_030666) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Synonyms
EI; ELANH2; HEL-S-27; HEL57; LEI; M/NEI; MNEI; PI-2; PI2
Gene ID
1992
UniProt
P30740, V9HWH1
Accession Number mRNA
NM_030666
Chromosomal Location
6p25.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
2670165128292880
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
42.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SERPINB1
Species
Human
Protein ID
NP_109591
Overview
Recombinant protein of human serpin peptidase inhibitor, clade B (ovalbumin), member 1 (SERPINB1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1992
Uniprot URL
https://www.uniprot.org/uniprot/P30740
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_030666
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_109591
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