Thymidine Phosphorylase (TYMP) (NM_001953) Human Recombinant Protein

Product Specifications

Background

This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]

Overview

Recombinant protein of human thymidine phosphorylase (TYMP), transcript variant 2

Synonyms

ECGF; ECGF1; hPD-ECGF; MEDPS1; MNGIE; MTDPS1; PDECGF; TP

Gene ID

1890

UniProt

P19971, E5KRG5

Accession Number mRNA

NM_001953

Chromosomal Location

22q13.33

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Bladder cancer, Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism

Field of Research

Bladder cancer, Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

49.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.