SH3KBP1 (NM_031892) Human Recombinant Protein

Product Specifications

Background

This gene encodes an adapter protein that contains one or more N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]

Overview

Recombinant protein of human SH3-domain kinase binding protein 1 (SH3KBP1), transcript variant 1

Synonyms

AGMX2; CD2BP3; CIN85; GIG10; HSB-1; HSB1; IMD61; MIG18

Gene ID

30011

UniProt

Q96B97, Q5JPT6

Accession Number mRNA

NM_031892

Chromosomal Location

Xp22.12

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Endocytosis

Field of Research

Endocytosis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

72.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.