SH3KBP1 (NM_031892) Human Recombinant Protein
Product Specifications
Background
This gene encodes an adapter protein that contains one or more N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]
Synonyms
AGMX2; CD2BP3; CIN85; GIG10; HSB-1; HSB1; IMD61; MIG18
Gene ID
30011
UniProt
Q96B97, Q5JPT6
Accession Number mRNA
NM_031892
Chromosomal Location
Xp22.12
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Endocytosis
Field of Research
Endocytosis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
72.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SH3KBP1
Species
Human
Protein ID
NP_114098
Overview
Recombinant protein of human SH3-domain kinase binding protein 1 (SH3KBP1), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/30011
Uniprot URL
https://www.uniprot.org/uniprot/Q96B97
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_031892
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_114098
Curated Selection
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