Butyrylcholinesterase (BCHE) (NM_000055) Human Recombinant Protein
Product Specifications
Background
This gene encodes a cholinesterase enzyme and member of the type-B carboxylesterase/lipase family of proteins. The encoded enzyme exhibits broad substrate specificity and is involved in the detoxification of poisons including organophosphate nerve agents and pesticides, and the metabolism of drugs including cocaine, heroin and aspirin. Humans homozygous for certain mutations in this gene exhibit prolonged apnea after administration of the muscle relaxant succinylcholine. [provided by RefSeq, Jul 2016]
Synonyms
BCHED; CHE1; CHE2; E1
Gene ID
590
UniProt
P06276
Accession Number mRNA
NM_000055
Chromosomal Location
3q26.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
68.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
BCHE
Species
Human
Protein ID
NP_000046
Overview
Recombinant protein of human butyrylcholinesterase (BCHE)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/590
Uniprot URL
https://www.uniprot.org/uniprot/P06276
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000055
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000046
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